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rheumatology differential causes classification dermatology erythematosus activation bruising comparison criteria druginduced eularacr glomerulonephritis macrophage mas nonpalpable palpable pediatrics peds petechiae
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Diagnosis Framework ... : - Thrombocytopenia ... Splenomegaly - CTD (SLE ... Dermatosis: Schamberg ... Associated - SLE
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
pericarditis • Hematologic ... II or V lupus nephritis ... lupus nephritis ... #Systemic #Lupus ... Erythematosus #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... and Management ... nephritis, NPSLE ... #lupus #Systemic
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... ) - SLE ( ... systemic lupus erythematosus ... infections - Vasculitis ... pediatrics #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... inflammation Others: • Lupus ... lupus erythematosus ... , and SLE) • Urinalysis ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... Henoch-SchonIein Purpura ... #differential #diagnosis ... #algorithm #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
months to years) Systemic ... nephritis, NPSLE ... Workup: - ANA ... #table #rheumatology ... #diagnosis #management
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... hemostasis: - Thrombocytopenia ... (lupus, RA, Sjogren's ... #Algorithm #Causes
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... diseases, such as SLE ... often causes arthritis ... - interstitial keratitis ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... [SLE], AOSD) • ... thrombocytopenia ... Activation #Syndrome #Diagnosis ... #Management #Hematology
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