25 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... , Polymyositis/Dermatomyositis ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Anti-Jo, +Anti-Mi2 Dermatomyositis ... joint aches • +ANA ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... , Drug-induced Lupus ... , Polymyositis/Dermatomyositis ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Management Summary ... 40, F:M 9:1 • Clinical ... Workup: - ANA ... #Summary #rheumatology
Psoriasiform Scalp Findings in Dermatomyositis

Scalp: DM patients can present with a psoriasiform scalp eruption characterized redness,
intense pruritus, and ... or seborrheic dermatitis ... #Scalp #sign #SkinRash ... #Dermatomyositis ... #Dermatology #Clinical
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Erythematosus (SLE) Clinical ... Diagnosis of Lupus ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Still disease, dermatomyositis ... Non-autoimmune rheumatologic ... lymphoproliferative syndrome Clinical
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Workup: - ANA ... 40, F:M 9:1 • Clinical ... Workup: - ANA ... comparison #table #rheumatology
Dermatomyositis with heliotrope rash, shawl sign, and Gottron's papules

A middle-aged man describes progressive difficulty combing his
Dermatomyositis ... this is a case of dermatomyositis ... Nutrient def. w dermatitis ... #heliotrope #skinrash ... #dermatology #clinical
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... inflammation Others: • Lupus ... lesions-interstitial keratitis ... such as systemic lupus ... #diagnosis #rheumatology