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aki rheumatology algorithm vasculitis injury casts kidneyinjury rpgn acutekidneyinjury cryoglobulins erythematosus failure interpretation postrenal prerenal progressive pulmonary rapidly renal sle
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... - Small vessel vasculitis ... glomerulonephritis ... necrosis (causes ... #diagnosis #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
) - Loss of kidney ... disease (hematuria ... nephritis, cryoglobulinemia ... #Differential # ... Diagnosis #Nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... , glomeruli, and ... Kidneys -> glomerulonephritis ... differential #diagnosis ... #rheumatology #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... • Limited to Kidney ... #Vasculitis #differential
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
alveolar hemorrhage + Glomerulonephritis ... polyangiitis, Microscopic ... , Cryoglobulinemia ... Complex: Systemic lupus ... diagnosis #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Acute Kidney Injury ... • Hepatorenal syndromes ... polyangiitis /microscopic ... Interstitial Nephritis
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
are seen in acute ... broad - Advanced kidney ... syndrome ("Maltese ... #Differential # ... Microscopy #Diagnosis
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
Acute Kidney Injury ... inhibitors, hepatorenal syndrome ... Post-infectious GN, Lupus ... Interstitial Nephritis ... Diagnosis #nephrology
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Causes of Acute ... Small-vessel vasculitis ... • Inflammatory disease ... #Acute #Kidney ... #Nephrology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Skin ulcers - Glomerulonephritis ... • Autoimmune diseases ... - GPA, EGPA, microscopic ... (e.g. systemic lupus ... #types #classification
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