13 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Gravis, Graves' Disease ... Lupus Erythematosus ... #Allergy #Allergic
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... during hemolytic disease ... lupus erythematosus ... Pathophysiology #Allergy
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
): - Allergic ... Rhinitis - Allergic ... Dermatitis - ... Lymphomas - Systemic ... #Causes #hematology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Classification of ... vasculitis - hypersensitivity ... lupus erythematosus ... #Rheumatology # ... Diagnosis
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... reaction, Haemolytic disease ... lupus erythematosus ... reactions #types #allergy ... #table #classification
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Reactive: - Systemic ... Lupus Erythematosus ... • Acne • Allergy ... Algorithm #Causes #Hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... released during an allergic ... basophilic leukemia Hypersensitivity ... Colitis and Crohn’s Disease ... #causes #hematology
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
#eczema #dermatology ... #skinrash References ... corticosteroids in dermatology ... Allergy. 2018;73 ... J Allergy Clin Immunol
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... disease. ... CANDLE syndrome - Allergic ... ’s syndrome - Lupus ... #dermatology #oncology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus ... • Drug-induced hypersensitivity ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology