12 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... Gravis, Graves' Disease ... • Ex: Systemic Lupus ... Syndrome, Contact Dermatitis ... #Allergy #Allergic
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... during hemolytic disease ... , and systemic lupus ... - Contact dermatitis ... sclerosis #Hypersensitivity
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
a.k.a. extrinsic allergic ... alveolitis): • Hypersensitivity ... ILD caused by inhalation ... Polymyositis-dermatomyositis, Lupus ... differential #pulmonary #causes
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
table of types of hypersensitivity ... lgE causes mast-cell ... reaction, Haemolytic disease ... glomerulonephritis, Systemic lupus ... Examples: Contact dermatitis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... Pigmented Purpuric Dermatosis ... : Schamberg Disease ... Vasculitis: • Hypersensitivity ... #rheumatology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Cerebrovascular Disease ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
released during an allergic ... basophilic leukemia Hypersensitivity ... Colitis and Crohn’s Disease ... Chickenpox Other Causes ... #hematology #basophils
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
, a disease with ... treatment #diagnosis #causes ... #dermatology #skinrash ... Allergy. 2018;73 ... J Allergy Clin Immunol
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... with systemic disease ... Causes: - Idiopathic ... CANDLE syndrome - Allergic ... ’s syndrome - Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... inflammation Others: • Lupus ... lesions-interstitial keratitis ... such as systemic lupus ... differential #diagnosis #rheumatology