19 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Gravis, Graves' Disease ... • Ex: Systemic Lupus ... Syndrome, Contact Dermatitis ... (ie. reaction to ... #Allergic #Reactions
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Bullous impetigo - Reaction ... • Contact dermatitis ... Bullous systemic lupus ... diabeticorum) - Reaction ... Vesiculobullous #SkinRash
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Involvement in Systemic Lupus ... Lupusreference #Renal #diseases ... SLE #Systemic #Lupus ... Erythematosus #venn #nephrology ... classification #types #rheumatology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... , Haemolytic disease ... glomerulonephritis, Systemic lupus ... Examples: Contact dermatitis ... #types #allergy
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... during hemolytic disease ... , and systemic lupus ... - Contact dermatitis ... #Diagnosis #Reactions
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... syndrome, POEMS • Reaction ... post-splenectomy, Exercise, Allergic ... reactions Matthew
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
released during an allergic ... reaction or asthma ... Or Inflammatory Reactions ... Colitis and Crohn’s Disease ... Diagnosis #causes #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Other: Transfusion reaction ... usually IgG) (e.g. lupus ... cold agglutin disease ... - Transfusion reaction ... differential #diagnosis #hematology
Peritoneal Dialysis Fluid Appearance and Color - Differential Diagnosis
 • Cloudy: Peritonitis, Intraperitoneal disease (appendicitis, cholecystitis,
Intraperitoneal disease ... Retroperitoneal disease ... amphotericin B), Allergic ... reaction (increased ... Differential #Diagnosis #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Cerebrovascular Disease ... Diagnosis of Lupus ... Erythematosus #SLE #CNS #neurology ... #rheumatology #