18 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Gravis, Graves' Disease ... • Ex: Systemic Lupus ... Syndrome, Contact Dermatitis ... #Allergic #Reactions ... Classification #Diagnosis
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
- Differential Diagnosis ... • Contact dermatitis ... Bullous systemic lupus ... Vesiculobullous #SkinRash ... #Differential #Diagnosis
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... , Haemolytic disease ... glomerulonephritis, Systemic lupus ... Examples: Contact dermatitis ... #types #allergy
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... post-splenectomy, Exercise, Allergic ... reactions Matthew
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... during hemolytic disease ... , and systemic lupus ... - Contact dermatitis ... #Diagnosis #Reactions
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... released during an allergic ... reaction or asthma ... Colitis and Crohn’s Disease ... #causes #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Other: Transfusion reaction ... usually IgG) (e.g. lupus ... #differential #diagnosis ... #hematology #anemia
Peritoneal Dialysis Fluid Appearance and Color - Differential Diagnosis
 • Cloudy: Peritonitis, Intraperitoneal disease (appendicitis, cholecystitis,
- Differential Diagnosis ... Intraperitoneal disease ... amphotericin B), Allergic ... reaction (increased ... #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... permeability Diagnosis ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
, a disease with ... medications #treatment #diagnosis ... #dermatology #skinrash ... Allergy. 2018;73 ... J Allergy Clin Immunol