13 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Erythematosus ... Lupusreference #Renal #diseases ... #venn #nephrology ... #nephritis #classification ... #types #rheumatology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Classification of ... - systemic lupus ... erythematosus ... dermatomyositis #Size #Classification ... Vessels #Diagnosis #Rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria ... IgA nephropathy, lupus ... Glomerulonephritis #RPGN #Classification ... Differential #Diagnosis #Nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematosus) ... Classification: ... erythematosus ( ... Non-autoimmune rheumatologic ... #Diagnosis #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... Cerebrovascular Disease ... #Erythematosus ... #SLE #CNS #neurology ... #rheumatology #
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
severity (ISN/RPS classification ... by 12 months Classification ... Focal LN (<50% of glomeruli ... treatment #management #rheumatology ... #nephrology
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Gravis, Graves' Disease ... • Ex: Systemic Lupus ... Erythematosus, ... Syndrome, Contact Dermatitis ... Reactions #Types #Classification
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Complex: Systemic lupus ... erythematosus, ... sclerosis • Anti-Glomerular ... Goodpasture's Disease ... differential #diagnosis #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: - Kidneys: glomerular ... such as systemic lupus ... erythematosus, ... differential #diagnosis #rheumatology ... #classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
during hemolytic disease ... , and systemic lupus ... erythematosus ... - Contact dermatitis ... Hypersensitivity #Types #Classification