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differential rheumatology clinical cryoglobulinemia cryoglobulins erythematosus lesions leukemia monoclonal myelodysplastic paraproteinemias pathology semiology signs skin sweet systemic types vasculitides
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... appearing during the disease ... Neutrophilic dermatosis ... dermatomyositis, SLE ... #dermatology #oncology
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... (10%) : SLE +++ ... #Vasculitis #dermpath ... #dermatology #semiology ... signs #lesions #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Erythematosus #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
such as systemic lupus ... strong sign of cutaneous ... , and SLE) • Urinalysis ... #rheumatology # ... classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... : - 10% SLE or ... Henoch-Schönlein purpura) • Cutaneous ... (e.g. systemic lupus ... #types #classification
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... - Lupus - Leukemia ... #diagnosis #dermatology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... : CNS manifestations ... violaceous, nontender cutaneous ... #Leukemia #Hematology ... #Oncology #Diagnosis
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