8 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... #CNS #neurology ... #rheumatology # ... #management #treatment
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Many others • Transverse ... myelitis: Motor ... pain • Extra-CNS ... (Systemic lupus ... #neurology #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... neuropathy • Transverse ... Myelitis • Psychosis ... Chronic B-cell activation ... #Rheumatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis ... Myelitis Diagnosis ... Myelitis Treatment ... #Myelitis #diagnosis ... #management #neurology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... erythematosus [SLE ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... myelitis • 8%- ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
sclerosis - Transverse ... myelitis - Neuromyelitis ... - SLE, Scleroderma ... MCTD, Sjogren syndrome ... #diagnosis #neurology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
including systemic lupus ... erythematosus (SLE ... Histopathological Diagnoses ... Hypoalbuminemia Treatment ... #management #rheumatology