14 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (SLE), Systemic ... • Rheumatic Diseases ... : Lupus (SLE), Systemic ... #Antibodies #ANA
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic ... Diseases: • Homogeneous ... connective tissue disease ... (SLE), Systemic ... #Antibodies #ANA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
) • Systemic lupus ... connective tissue disease ... 90% • Anti-GBM disease ... #Antinuclear #Antibody ... diseases
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
polychondritis, Behcet's Disease ... Nodosa (PAN), ANCA ... Diseases: IgG4- ... Related Disease ... Systemic lupus
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Discoid Rash A Antinuclear ... Antibody (ANA) ... R Renal Disease ... #IMDAMNSHARP #sle ... #systemic #lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pain • Kawasaki Disease ... (Granulomatous disease ... rheumatic diseases ... atherosclerotic disease ... most important diseases
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Peripheral edema, Disease-specific ... disease, Cryoglobulinemia ... , Rheumatoid arthritis ... Goodpasture's Disease ... dysmorphic RBCs) • Disease-specific
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Antiphospholipid-antibody ... , Lyme disease, ... Vasculitis (e.g. ... #joint #pain #differential ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
infection • Lyme disease ... migrans • Lyme disease ... rheumaticum • Rheumatic ... Sarcoidosis • Crohn's disease ... Antiphospholipid-antibody
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... vasculitis, rheumatoid ... Still disease, ... diseases (i.e. ... #Systemic #Lupus