12 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... antibodies) • Systemic ... lupus erythematosus ... in drug-induced SLE ... • Sjögren syndrome
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
(CNS) involvement ... Inflammatory causes ... • Systemic lupus ... vasculitides • ... #differential #
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... , Loose anagen syndrome ... DHEAS) • ANA ... Vitamin D levels Systemic ... Diagnosis #dermatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... arteritis, Cogan's Syndrome ... Arthritis (RA), Systemic ... lupus erythematosus ... (SLE), Sarcoidosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia ... Differential ... and CNS • Headache ... #Systemic #Lupus
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Pigmented Purpuric Dermatosis ... Associated - SLE ... #Diagnosis #hematology ... #nonpalpable #dermatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... #SLE #CNS #neurology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Scleromyxedema (CNS ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... Others: • Lupus ... lupus erythematosus ... , and SLE) • Urinalysis ... #rheumatology #
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... Vasculitis: •