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rheumatology differential ana classification thrombocytopenia anca antibody aortitis bee bruising causes cryoglobulinemia cryoglobulins diseases inflammatory management neurology patterns pediatrics peds
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... erythematosus ... ANCA-Associated Vasculitis ... Renal-limited vasculitis ... #antibodies #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... : Lupus (SLE), Systemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ANCA-associated vasculitis ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... #Systemic #Lupus
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... arteritis, Cogan's Syndrome ... ANCA associated vasculitis ... lupus erythematosus ... (SLE), Sarcoidosis
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
central nervous system ... • Systemic lupus ... erythematosus ... optica spectrum disorder ... ANCA-associated vasculitides
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• IgA vasculitis ... Hypersensitivity vasculitis ... • Vasculitis ... lupus erythematosus ... #rheumatology #vasculitis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... as systemic lupus ... erythematosus, ... C-ANCA) pattern: antibodies ... , and SLE) • Urinalysis
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
(systemic lupus ... erythematosus) ... Congenital heart disease ... infections - Vasculitis ... peds #pediatrics #diagnosis
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
, including systemic ... lupus erythematosus ... (SLE), Sjögren’ ... vasculitis - Infectious ... in LNs and the systemic
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