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management hematology neurology ana antinuclear causes signs sle vasculitis activation acute algorithm antibodies atlas autoantibodies beaus behcet cardiology cerebritis classification
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... and treatment can ... • Systemic lupus ... #Syndromes #neurology ... differential #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Lupus Erythematosus ... (SLE) Clinical ... Demyelinating Syndrome ... : • Inflammatory ... #Lupus #Erythematosus
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Wiskott-Aldrich syndrome ... • Lymphoma Inflammatory ... : • Systemic lupus ... erythematosus ... #Diagnosis #Hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... • Systemic lupus ... Periodic fever syndromes ... lupus erythematosus ... hypersensitivity syndromes
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
BEE Syndromes - ... and treatment can ... recessive—Usher syndrome ... MS • Other • Syndromes ... #Syndromes #neurology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
for Sweet Syndrome ... onset of tender erythematous ... disease, or pregnancy ... Abnormal laboratory ... neutrophils #Sweet #Syndrome
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Can also be measured ... -15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... #lupus #erythematosus ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Mucocutaneous lymph node syndrome ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... lupus erythematosus ... #diagnosis #rheumatology
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