10 results
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Syndromes and Mimics ... ANCA Associated Vasculitis ... , Rheumatoid Vasculitis ... Renal Crisis, IgA Vasculitis ... syndrome in APL
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
BEE Syndromes - ... • Systemic lupus ... ANCA-associated vasculitides ... #neurology #inflammatory ... #differential #
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Syndrome Definition ... Renal Syndromes ... ANCA-positive vasculitis ... ANCA-negative vasculitis ... IgA-associated vasculitis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Mucocutaneous lymph node syndrome ... : • Behçet Syndrome ... • Cogan Syndrome ... : - Ocular inflammatory ... such as systemic lupus
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Syndrome in APML ... febrile neutrophilic dermatosis ... Imaging: CXR- pulmonary ... initiation • Differential ... #Syndrome #APML
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
disease, Leprosy • Inflammatory ... Guillain-Barre, Vasculitis ... , Sjogren's, Lupus ... Paraprotein-associated (POEMS syndrome ... Fabry's disease, Acute
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Mucocutaneous lymph node syndrome ... • Behcet syndrome ... • Cogan syndrome ... : Ocular inflammatory
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
stroke syndromes ... : Vasculitis • ... Paraneoplastic syndrome ... Lambert-Eaton - Isaacs' syndrome ... anti-Jo-1] - (Vasculitis
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Autoimmune ANCA vasculitis ... Renal Syndromes ... palpable purpura 2/2 vasculitis ... #Renal #Syndromes
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Culture Positive: • Acute ... Cerebral > Splenic, Pulmonary ... valvular disease • Vasculitis ... Cholesterol emboli syndrome ... hematuria, + RF Treatment