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diagnosis hematology management oncology algorithm cancer causes acquired chronic cll differentiation dress hyperviscosity immune inflammatory iris leukemia lymphocytic mds mintc
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Triggers: ATRA treatment ... initiation • Differential ... Renal Failure Treatment
Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Hyperviscosity Syndrome ... - Causes and Treatment ... hyperleukocytosis (AML ... #Causes #Differential ... #Diagnosis #Treatment
Approach to the Rash in a an oncology patient - MINT-C Mnemonic M - Malignancy: Leukemia cutis,
Dermatoses: Sweet Syndrome ... Gangrenosum, NEH T - Treatment ... Rash #oncology #differential ... MINTC #Mnemonic #dermatology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... vonWillebrand #Syndrome ... Diagnosis #Management #treatment ... #hematology #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Thrombocytosis #Platelets #Differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome ... workup #oncology #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Resolution > 15 days Differentials ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... leukoencephalopathy (PML ... Leishmaniasis Differential ... #Inflammatory #Syndrome ... #Differential #
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Neutropenia - Differential ... hypertension and/or drug treatment ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... diagnosis #causes #hematology
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