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diagnosis hematology algorithm oncology management classification disorders syndrome biopsy chronic cll comparison differentiation dress eosinophil eosinophilia hodgkins indications leukemia lymphoma
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... microglobulin Treatment ... Transform to DLBCL, PML ... Leukemia #diagnosis #workup ... #oncology #hematology
Initial triage of the neutropenic adult - Algorithm for the evaluation and treatment of adult patients
evaluation and treatment ... neutropenia #Algorithm #workup ... #diagnosis #hematology ... #indications #differential
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Responsive to Treatment ... growth, response to treatment ... pathophysiology #Hematology ... Diagnosis #NonHodgkin #differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... initiation • Differential ... Renal Failure Treatment ... Differentiation #Syndrome #APML
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... glucocorticoid treatment ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... for workup, including ... Rebound effect from treatment ... Thrombocytosis #Platelets #Differential
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Atypical Lymphocytes ... Resolution > 15 days Differentials ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
HL (MCHL) - Lymphocyte ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
Like Conditions - Differential ... biopsy demonstrates lymphocytes ... the mainstay of treatment ... #Scleroderma #Differential ... comparison #table #dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... blood count with differential ... Syndromes #diagnosis #hematology
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