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diagnosis hematology oncology causes chronic differentiation hemeonc hemophagocytic hlh hyperviscosity leukemia lymphocytic lymphohistiocytosis mds myelodysplasia myelodysplastic syndromes workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Cytopenias: • Neutropenia ... microglobulin Treatment ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome
Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Hyperviscosity Syndrome ... transformation (CML ... hyperleukocytosis (AML ... #Causes #Differential ... #Management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... • Induce blast cell ... initiation • Differential ... #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease • Neutropenia ... factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... #diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... hypertension and/or drug treatment ... , Kostmann syndrome ... Chediak-Higashi syndrome ... #differential #
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... with the HLH syndrome ... thrombocytopenia, neutropenia ... #Hematology #HemeOnc
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