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hematology differential management cancer hepatology hepatopulmonary leukemia amiodarone bronchiectasis cardiology causes chronic cirrhosis cll differentiation endocarditis essential et hps induced
Causes of Dyspnea - Differential Diagnosis Algorithm Cardiac: • Dysrhythmia • Ischemia • Cardiomyopathy • Valvular disease
Causes of Dyspnea ... - Differential Diagnosis ... Algorithm Cardiac ... Superior vena cava syndrome ... • Interstitial lung
Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion
Dyspnea - Considerations ... Lymphangitic spread to lung ... metastases Treatment ... #algorithm #differential ... #diagnosis #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... #APML #diagnosis ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Bone pain, dyspnea ... smear: Blasts APML ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... absence of intrinsic lung ... Presentation: • Dyspnea ... • Platypnea - Dyspnea ... on radioactive lung
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
• Hypoxia • Dyspnea ... • Mounier-Kuhn syndrome ... in the adjacent lung ... of the affected lung ... mycobacteria Treatment
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
• Amiodarone half ... starting amiodarone treatment ... respiratory distress syndrome ... Dyspnea 3. ... macrophages Treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... microglobulin Treatment ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology ... #oncology
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
presence in the lower lung ... • Progressive dyspnea ... the left heart TREATMENT ... only definitive treatment ... #cirrhosis #diagnosis
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