10 results
diagnosis hematology prolonged algorithm treatment apml arterial bleeding bruising dic differentiation disorders disseminated embolism hemophilia hemostasis inr intravascular microangiopathy oncology
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
PT (INR), Normal ... PTT, Normal PT ... , Normal PT (INR ... #INR #Differential ... #Hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... #PT #aPTT #Prolonged ... #differential # ... hematology #coagulation
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal • ... #Algorithm #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... PT and the aPTT ... amyloidosis #Abnormal ... #PT #aPTT #Prolonged ... hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... protein C and S Pathophysiology ... INR < 2.3 - APTT ... #treatment #management ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... #Diagnosis #Hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... mixing study (aPTT ... mild cases) • ... PT/INR & von Willebrand ... #treatment #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... intravascular coagulation ... and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
be performed PT ... , PTT, and fibrinogen ... decrease in most cases ... WBC count and differential ... Diagnosis #Workup #Hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
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