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diagnosis algorithm anemia coagulation management pt abnormal intravascular platelets anticoagulation aplastic apml arterial atlas bleeding breakthrough bruising cd4 dic differentiation
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PTT • Prolonged ... #PPT #PT #INR #Differential ... Diagnosis #Algorithm #Causes ... #Hematology #coagulation
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... specifically: iron deficiency ... Myelodysplastic syndrome ... #hematology #secondary
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... malignancy • Iron deficiency ... #Differential # ... #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... #Prolonged #Causes ... #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... for a Prolonged ... #Prolonged #Causes ... #diagnosis #differential ... #hematology #coagulation
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - ... Differential Diagnosis ... blood loss (Fe deficiency ... Diagnosis #causes ... #Platelets #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... Acute hemolysis, deficiency ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... • Folate Deficiency ... Non-lmmune: • HELLP Syndrome ... #Hematology
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
- Antithrombin deficiency ... Structural - Pelvic masses ... - May-Thurner syndrome ... anticoagulation #hematology ... #differential #
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Dyspnea - Differential ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... #dyspnea #sob #differential ... #pulmonary
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