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algorithm classification oncology aplastic disorders elevatedmcv globulin leukocytosis macrocytic macrocytosis management mds morphologic myelodysplasia neutropenia nonpalpable palpable platelet protein proteingap
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
with Pancytopenia ... - Differential ... Toxins • Aplastic Anemia ... • Myelodysplasia ... #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Approach - MCV) ... Hypothyroidism, Myelodysplastic ... #differential # ... diagnosis #causes ... #hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Approach to Leukocytosis ... hepatomegaly • Labs: anemia ... , ↑ MCV, ↑/↓ platelets ... #hematology #WBC ... #Leukemoid
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Poisoning • Anemia ... Marrow Failure • Anemia ... #Anemia #MCV ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
to Anemia - Differential ... Deficiency • Aplastic Anemia ... • Anemia of Chronic ... Non-lmmune #Anemia ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Pernicious Anemia ... • Pernicious Anemia ... #Macrocytic #Anemia ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... vera (PV) • Myelodysplastic ... Chronic myeloid leukemia ... #Diagnosis #Causes ... #hematology #secondary
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... changes), high MCV ... anemia (vegan, ... #Diagnosis #Causes ... #Workup #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Immune Aplastic Anemia ... and petechiae Causes ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... Anemia • Bone ... Megaloblastic Anemia ... Myelophthisic Anemia ... #hematology #oncology
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