16 results
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... in Hemolytic Anemia ... #Laboratory #Testing ... #workup #diagnosis ... #hematology #hemolysis
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic Anemia ... Differential Diagnosis Table ... Autoimmune #Hemolytic #Anemia ... Differential #Diagnosis #Table ... #hematology
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing

SUMMARY:
 - RDW, FEP, serum iron,
Disease - Laboratory ... Testing SUMMARY ... marrow iron stain-"gold ... #Testing #Comparison ... #Table #Fe
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Warm vs Cold Autoimmune ... Immunosuppression, Splenectomy Cold ... BostonChiefs #Warm #Cold ... #hematology #diagnosis ... #comparison
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... a clinical and laboratory ... Microangiopathic hemolytic anemia ... coagulation and other testing ... #Hematology #Pathology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
awaiting confirmatory testing ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Agglutination - Cold ... ARUPLabs #Hemolytic #Anemia ... Diagnosis #Algorithm #workup ... #hematology #testing
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Autoimmune: Warm AIHA, Cold ... Defects: Sickle cell anemia ... Hypophostphatemia Laboratory ... Differential #Diagnosis #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... Eating disorders ... Acquired Aplastic Anemia ... #Pancytopenia #Workup ... Diagnosis #Algorithm #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... Positive Coombs testing ... disease #hemolytic #anemia ... #hematology #diagnosis