16 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... - infiltrates (anemia ... ) CLL Symptoms: ... -> Invade Skin: ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Hepatomegaly • Skin ... • Neutropenia, anemia ... diagnosis #workup #oncology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
red-flags to exclude dermatologic ... , vital sign instability ... sulfa-drug - Skin ... #Diagnosis #Dermatology ... Maculopapular #Scaling
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... yrs old; F>M Signs ... - Normocytic Anemia ... - Vasculitic skin ... Temporal #Arteritis #Pathophysiology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
UV light Incr cell ... inflammation on skin ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Headaches • Pale skin ... Constitutional Syndromes ... • Improve the symptoms ... #oncology #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and Symptoms: ... symptoms by days ... #diagnosis #dermatology ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... count (anemia) ... just beneath the skin ... #diagnosis #hematology ... #oncology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
integrity of: • Skin ... breath, wasting, anemia ... Psychiatric symptoms ... Loss of teeth Anemia ... Muscle cramping Skin
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... (-) hemolytic anemia ... Differential #Diagnosis #Oncology