28 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... • Immunologic Workup ... Evolution: Chronic disease ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Cerebrovascular Disease ... , PRES Pathophysiology ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
COVID-19: ICU Guidelines for the Non-Intensivist
Infection Control
Risk Factors for Severe Disease
Initial Laboratory Workup
COVID-19 Specific Medications
Respiratory
Cardiac
Hematologic
Neuro/Sedation

#COVID19 #ICU
Factors for Severe Disease ... Initial Laboratory Workup ... Respiratory Cardiac Hematologic ... NonIntensivist #diagnosis #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... with more severe disease ... #Systemic #Lupus ... Summary #diagnosis #rheumatology ... #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... Usual therapeutic management ... Evolution: Chronic disease ... #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... menstrual - Recent ... PT, aPTT(liver disease ... Diagnosis #Causes #Workup ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Common European descent ... 65 years PBC Pathophysiology ... but elevated as disease ... cholangitis #diagnosis #workup ... #hepatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Post-strep GN, Lupus ... involvement: Anti-GBM Disease ... diagnosis #algorithm #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... • Systemic lupus ... SJIA], systemic lupus ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... IgG4 #Related #Disease ... #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology