9 results
Practical Approach to Grading Diastolic Dysfunction

#Diagnosis #Cardiology #Diastolic #Diastology #Dysfunction #Grading #Classification #Grades #Criteria #Algorithm #Assessment
Grading Diastolic Dysfunction ... Diastolic #Diastology #Dysfunction ... #Grading #Classification ... #Grades #Criteria ... #Algorithm #Assessment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Presentation: • Rapid development ... nervous system (CNS) dysfunction ... Histopathologic criteria ... #Macrophage #Activation
Guide to systemic mastocytosis

Criteria for diagnosis: at least 1 major and 1 minor or 3 minor
mastocytosis Criteria ... minor or 3 minor criteria ... cytopenias or meeting criteria ... without organ dysfunction ... hemepath #pathology #algorithm
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... progressive organ dysfunction ... • Essential Criteria ... complement • Classification ... 2019 ACR/EULAR Criteria
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
sympathetic + ADH activation ... Diagnosis (Clinical Criteria ... Classification: ... Norepinephrine may ... be substituted as
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
allergens and activate mast ... allergen causes development ... because T-Cell activation ... Reactions #Types #Classification
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... Persistent fever, organ dysfunction ... (often termed MAS-HLH ... Diagnostic Criteria ... of 8 HLH-2004 criteria
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... erythematosus (NPSLE): • May ... mild cognitive dysfunction ... Chronic B-cell activation
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
does not meet criteria ... misclassified as ... and cytometry as ... guide subtype classification ... Complement pathway activation