11 results
Practical Approach to Grading Diastolic Dysfunction

#Diagnosis #Cardiology #Diastolic #Diastology #Dysfunction #Grading #Classification #Grades #Criteria #Algorithm #Assessment
Practical Approach to Grading ... #Dysfunction #Grading ... #Classification ... #Grades #Criteria ... #Algorithm #Assessment
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
, seasonal hay fever ... cellular antigen, leading ... to complement activation ... Complement activation ... #Classification
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
Pathogenesis of Rheumatic Fever ... Pathogenesis of rheumatic fever ... to the development ... by endothelial activation ... Exposure of Type-IV
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of types ... Anaphylaxis, Hay fever ... cell antigens, leading ... to complement activation ... allergy #table #classification
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... degranulation, leading ... allergen causes development ... because T-Cell activation ... #Classification
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... IL-1 and IL-6, leading ... Presentation: • Rapid development ... Histopathologic criteria ... MAS #Macrophage #Activation
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
sympathetic + ADH activation ... Diagnosis (Clinical Criteria ... Classification: ... HRS-AKI (formerly Type ... HRS-Non-AKI (formerly Type
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Skin Disease Classification ... Kikuchi disease • Type-I ... to: Arthritis, Fever ... Chronic B-cell activation
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
by uncontrolled activation ... Types of HLH • ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... Fever b.
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
does not meet criteria ... guide subtype classification ... Complement pathway activation ... vasculitis Types