11 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... duration), Several medications ... hepatitis #DILI #DrugInduced ... #Diagnosis #Algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... , HSV, VZV • Medications ... valproate, azoles), Drugs ... #hepatology #algorithm ... Transaminitis #LFTs
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Chronic - ongoing ↑ LFTs ... gastroenterology #algorithm ... gastroenterology #hepatology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Discoloration • Medications ... heart failure • Diabetes ... Mellitus Half-and-Half ... #Differential #Diagnosis ... #Algorithm #causes
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Drug Induced Systemic ... Lupusreference #DrugInduced ... Erythematosus #medications ... #differential #diagnosis ... #rheumatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... the decision for ... ; T2DM, type 2 diabetes ... #LFTs #Abnormal ... #Algorithm #Hepatology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Trauma/Crush injury ... reactions Common Drugs ... (Uncontrolled diabetes ... - Metabolic acidosis ... Medications 2.
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
liver or renal injury ... circulation If drugs ... of Circulatory System ... • Type B1: - Diabetes ... - HIV/HAART medications
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Trauma/Crush injury ... reactions Common Drugs ... (Uncontrolled diabetes ... - Metabolic acidosis ... Medications 2.
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Acidosis B. ... neuromuscular injury ... Diabetes, diabetic ... oliguric kidney injury ... #Differential #Diagnosis