13 results
Mechanisms of thiazide diuretic side effects

Dr. Muner Mohamed @MunerMohamed1

#thiazide #diuretic #pharmacology #pathophysiology #sideeffects #adverseeffects #nephrology
#thiazide #diuretic ... #pharmacology # ... pathophysiology ... #sideeffects #adverseeffects ... #nephrology
Nephron - Diuretic Sites of Action

Source Text: https://www.sciencedirect.com/book/9780323449427/critical-care-nephrology#book-info

#Nephron #Diuretics #Site #Action #Location #Nephrology #Pathophysiology #Pharmacology
Nephron - Diuretic ... /critical-care-nephrology ... Action #Location #Nephrology ... #Pathophysiology ... #Pharmacology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... - Diuretic Sites ... Adenosine #Nephron #Pathophysiology ... #Action #nephrology ... #pharmacology
Mechanism of Action of Diuretics
Amiloride, Triamterene, Spironolactone
Loop Diuretics
Thiazides
Acetazolamide

#Diuretics #Mechanism #Action #pharmacology #pathophysiology #nephrology
Mechanism of Action of Diuretics ... Acetazolamide #Diuretics ... Mechanism #Action #pharmacology ... #pathophysiology ... #nephrology
Polyuria - Differential Diagnosis Algorithm
Urine Output > 3L /day
Water Diuresis (Urine Osm <100 mOsm/kg)
 • Primary
Differential Diagnosis Algorithm ... Polydipsia • Central Diabetes ... • Nephrogenic Diabetes ... Differential #Diagnosis #Algorithm ... #causes #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... • Nephrogenic diabetes ... Lithium-induced nephrogenic diabetes ... DDAVP) • Central diabetes ... #Nephrology #Pharmacology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Diagnosis Workup Algorithm ... • Hypovolemic: Diuretics ... osmotic (solute) diuresis ... • Euvolemic: Diabetes ... #nephrology #sodium
Polyuria - Differential Diagnosis Algorithm
Polyuria = >3L Urine output / 24 hours
Urine osmolality = 2 (Na
Differential Diagnosis Algorithm ... mosm/kg • Solute Diuresis ... 100 mosm/kg • Diabetes ... Differential #Diagnosis #Algorithm ... #nephrology
Causes of Polyuria - Differential Diagnosis Algorithm
Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min)
Osmotic
Differential Diagnosis Algorithm ... /min) Osmotic Diuresis ... (Uncontrolled Diabetes ... #Polyuria #Nephrology ... Differential #Diagnosis #Algorithm
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Differential Diagnosis Algorithm ... administration • Osmotic diuresis ... 300 mmol/kg • Diabetes ... Hypernatremia #Nephrology ... Differential #Diagnosis #Algorithm