30 results
Mechanisms of thiazide diuretic side effects

Dr. Muner Mohamed @MunerMohamed1

#thiazide #diuretic #pharmacology #pathophysiology #sideeffects #adverseeffects #nephrology
#thiazide #diuretic ... #pharmacology # ... pathophysiology ... #sideeffects #adverseeffects ... #nephrology
Nephron - Diuretic Sites of Action

Source Text: https://www.sciencedirect.com/book/9780323449427/critical-care-nephrology#book-info

#Nephron #Diuretics #Site #Action #Location #Nephrology #Pathophysiology #Pharmacology
Nephron - Diuretic ... /critical-care-nephrology ... Action #Location #Nephrology ... #Pathophysiology ... #Pharmacology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... - Diuretic Sites ... Adenosine #Nephron #Pathophysiology ... #Action #nephrology ... #pharmacology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... • Osmotic diuresis ... • Central diabetes ... • Nephrogenic diabetes ... #nephrology #sodium
Mechanism of Action of Diuretics
Amiloride, Triamterene, Spironolactone
Loop Diuretics
Thiazides
Acetazolamide

#Diuretics #Mechanism #Action #pharmacology #pathophysiology #nephrology
Mechanism of Action of Diuretics ... Acetazolamide #Diuretics ... Mechanism #Action #pharmacology ... #pathophysiology ... #nephrology
Diabetes – diabetic nephropathy
Majority of the literature in the area is applied to the diabetic nephropathy
Diabetesdiabetic ... applied to the diabetic ... be the primary cause ... - Cytokines #Pathophysiology ... #Nephrology #CKD
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
• Nephrogenic diabetes ... Kidney stones caused ... Lithium-induced nephrogenic diabetes ... DDAVP) • Central diabetes ... #Nephrology #Pharmacology
Polyuria - Differential Diagnosis Algorithm
Urine Output > 3L /day
Water Diuresis (Urine Osm <100 mOsm/kg)
 • Primary
3L /day Water Diuresis ... Polydipsia • Central Diabetes ... • Nephrogenic Diabetes ... Diagnosis #Algorithm #causes ... #nephrology
Causes of Polyuria - Differential Diagnosis
Excess Intake of Water:
 • Primary polydipsia (a.k.a. "psychogenic polydipsia")
 •
Causes of Polyuria ... a.k.a. osmotic diuresis ... : Conventional diuretics ... Diabetes Insipidus ... #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... (treatment of diabetic ... , Osmotic diuresis ... #Hypokalemia #Causes ... differential #diagnosis #nephrology