20 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... : high fever, CRP ... #AOSD #rheumatology ... #diagnosis #management ... #treatment
Evaluation and Management of Pediatric Fever #Diagnosis #Management #EM #Peds #Fever #Workup #Evaluation #Discharge #Admission #Algorithm
of Pediatric Fever ... #Diagnosis #Management ... #EM #Peds #Fever ... Discharge #Admission #Algorithm ... #Ddxof
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Differential Diaqnoses ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
- Differential Diagnosis ... , Severe Valve Disease ... • Obstructive: Pulmonary ... #criticalcare #algorithm ... #treatment #management
Cryptogenic Organizing Pneumonia - Illness Script

PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Cough, dyspnea, fever ... , neoplastic) TREATMENT ... steroids for severe disease ... TylerLarsenMD #COP ... #management #pulmonary
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Labs: • ↑ESR/CRP ... Treatment - Mild ... #AOSD #diagnosis ... #rheumatology # ... management
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... <10,000/mm3 - CRP ... < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Periodic fever ... erythematosus [SLE], AOSD ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... old on day ≥7 of fever ... echo is positive, treatment ... and lab signs (CRP ... #Diagnosis #Peds
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
night sweats, fever ... Cerebral > Splenic, pulmonary ... Criteria • ↑ ESR, CRP ... Persistent bacteremia/fevers ... #management #cardiology