6 results
management disease stills adultonset oncology syndrome activation adult apml differentiation emergencies hemeonc macrophage mas oncologic onset
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
: High spiking fever ... maculopapular rash ... : high fever, CRP ... #rheumatology # ... #treatment
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
extremities during febrile ... Treatment - Mild ... : NSAIDS Treatment ... Stills #disease #AOSD ... #diagnosis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... arthritis, Skin rash ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... erythematosus [SLE], AOSD ... Treatment: • Corticosteroids ... #Management #Hematology ... #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... Imaging: CXR- pulmonary ... #management #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
work-up - If febrile ... syndrome): - Hematologic ... , rash, hypoxia, ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
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