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management disease adultonset aosd dermatology oncology syndrome activation adult antinxp2 antinxp2dm apml cancer central dermatomyositis differential differentiation emergencies hemeonc macrophage
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... arthritis, Skin rash ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... maculopapular rash ... #AdultOnset #Stills ... Disease #AOSD #rheumatology ... #treatment
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... extremities during febrile ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Maculopapular Rashes - THE ALGORITHMIC APPROACH The term maculopapule is a portmanteau, a combination of macule and
Maculopapular Rashes - THE ALGORITHMIC ... appear toxic and febrile ... pathognomonic for SJS or EM ... #Diagnosis #Dermatology ... #Algorithm #Central
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Rare: DAH, acute febrile ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... #management #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Adult-onset Still ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... #Management #Hematology ... #Rheumatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
work-up - If febrile ... syndrome): - Hematologic ... - CRS: fever, rash ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
But can still have ... (blue-purple) rash ... • Erythematous rash ... positive patients Treatment ... #management #rheumatology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... algorithm 2018. ... median age at diagnosis ... cardiovascular or pulmonary ... #algorithm #hematology
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