11 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... #Acute #Chronic ... Failure #Cirrhosis #Hepatology ... #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... Infectious: • Acute ... effect following treatment ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... Rebound effect from treatment ... • Infections: Chronic ... #Algorithm #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
- Acute Bleeding ... Chronic Management ... Avoid meds that ... #Management #treatment ... #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... Algorithm DILI ... non-essential drug/HDS treatments ... dechallenge • Acute ... #Algorithm #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
B - Diagnosis and ... Management Algorithm ... HepatitisB #HBV #Algorithm ... #Diagnosis #Management ... #Treatment #Hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... • Rare: DAH, acute ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... #management #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... - Symptoms of chronic ... Hepatitis (eg Viral) Management ... regarding need for treatment ... #Management #Hepatology
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
Hypertension Presence of pulmonary ... obvious causes (chronic ... RVSP) - Estimates pulmonary ... pressure < 15mmHg TREATMENT ... #management #hepatology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
(ET) ET is a chronic ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology