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differential management erythematosus lupus marantic sle table arteritis autoimmune bony gca giantcell infectiousdiseases infective myopathy myositis nbte noninfective pericarditis presentation
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... Pericarditis, Endocarditis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Malignant Bone Tumors: Pathogenesis of X-ray appearance • Metastatic bone tumors (aka. cancerous cells from systemic
cancerous cells from systemic ... • Lung. thvroid ... Signs/Symptoms: ... #Malignant #Radiology ... #Diagnosis #XRay
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... /symptoms or echo ... Autoimmune (SLE/APLS), Malignancy ... in up to 30% of cases ... #comparison #infective
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Non-Infectious (NTBE): • Malignancy ... verrucous) • Lung ... Vascular: • Systemic ... Septic Emboli Cause ... #cardiology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
presentation of systemic ... life-threatening causes ... #Signs #Presentation ... #comparison #Table ... #Diagnosis
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 Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
signs/sx of inflammation ... vs infection vs malignancy ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Symptoms #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Infections • Malignancy ... • Libman-Sacks endocarditis ... Induced Lupus: • Symptoms ... #Rheumatology
Marantic Endocarditis Epidemiology: - Incidence of non-bacterial thrombotic endocarditis (marantic endocarditis if associated with cancer) is
patients with no signs ... - Lung, Pancreas ... Clinical Findings - Systemic ... #Diagnosis #Management ... #Cardiology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Non-Infectious (NTBE): • Malignancy ... , verrucous) - Lung ... Vascular: • Systemic ... Septic emboli cause ... #cardiology #infectiousdiseases
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Symptoms (SX) in ... purpura: Strong sign ... tract, and often causes ... exposure or Dx of malignancy ... #Rheumatology
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