11 results
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
and Bone Marrow Failure ... Telemore Biology Disorders ... #Syndromes #BoneMarrow ... #anemia #diagnosis ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Algorithm Consumption ... Disorders 1. ... Acquired Aplastic Anemia ... Congenital bone marrow failure ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Algorithm Consumption ... Disorders 1. ... Acquired Aplastic Anemia ... Congenital bone marrow failure ... #Algorithm #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Algorithm Low ... 80-100 fL) • Bleeding ... Hemolysis • Marrow Failure ... #MCV #Classification ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... changes), high MCV anemia ... - Bone marrow evaluation ... ITP, unexplained pancytopenia ... Causes #Workup #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... #Classification ... #Algorithm #Causes ... #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
bone marrow + pancytopenia ... ecchymoses, mucosal bleeding ... Inherited marrow-failure ... #oncology #hematology ... #diagnosis #management
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... administration, evaluation ... suggests liver failure ... #Differential #Diagnosis ... #Hematology
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
amyloidosis, or related disorder ... • New-onset anemia ... pain, abnormal bleeding ... Electrophoresis #SPEP #Hematology ... #Diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... are caused by bleeding ... • Bone Marrow Failure ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology