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disorders oncology leukemia anemia blood chronic cll enlarged eosinophilia extravascular hemolysis hodgkins intravascular lymphocytic lymphomas management markers nonhodgkin pathophysiology spleen
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... evaluation or workup ... (common causes ... #Differential # ... diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
microangiopathy: Thrombotic thrombocytopenic ... e.g. lupus, CLL, lymphoma ... agglutin disease, lymphoproliferative ... #differential # ... diagnosis #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Diagnosis Algorithm ... Malignant • Lymphoma ... Serum Sickness Hemolytic ... #Diagnosis #Algorithm ... #Causes #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphomas and Lymphoproliferative ... Diagnosis Algorithm ... (NHL) ~60% - lymphadenopathy ... pattern of spread, B symptoms ... pathophysiology #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm ... ALL) - PAS, TdT Lymphadenopathy ... (-) - Polycythemia ... Blood #Disorders #hematology ... #Diagnosis #Algorithm
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... and other C Cell lymphoproliferative ... Neutropenia, anemia, thrombocytopenia ... #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... ingestion • B symptoms ... Workup: • Full ... #diagnosis #classification ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • (Peripheral eosinophilia ... infiltrates (anemia, thrombocytopenia ... #Leukemia #Hematology ... #Oncology #Diagnosis
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