15 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Secondary ... disordersDiagnosis ... and Treatment Algorithm ... #HES #Hematology ... eosinophils #diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... • Screen for secondary ... causes of eosinophilia ... #Differential # ... diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... (HES) - Diagnosis ... Secondary Causes ... #diagnosis #hematology ... #differential #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Diagnosis Secondary ... Chronic inflammatory disorders ... Myelodysplastic syndrome ... #Diagnosis #Causes ... #hematology #secondary
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Diagnosis Framework ... ESRD & CAD • Eosinophilic ... GI Disorders ... cell activation syndrome ... #Diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... , Seizure disorders ... autoantibodies that will cause ... inflammation, leading ... CNS #neurology #rheumatology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential ... Diagnosis Neonate ... hypertension and/or drug treatment ... #diagnosis #causes ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Hemostasis - Differential ... Diagnosis Framework ... von Willebrand syndrome ... discern these causes ... #Diagnosis #Hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Paradoxical spontaneous bleeding ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #rheumatology # ... hematology