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rheumatology treatment algorithm als amyotrophic antibodies antinuclear bee cerebritis cord manifestations neuromyelitis optica patterns spinal spinalcord transverse vasculitis
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
(CNS) involvement ... Inflammatory causes ... • Systemic lupus ... • Multiple sclerosis ... #neurology #inflammatory
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... Syndrome (SS), ... : Lupus (SLE), Systemic ... Arthritis, Sjögren Syndrome
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... SLE) Clinical ... Demyelinating Syndrome ... #Lupus #Erythematosus ... #SLE #CNS #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Other brainstem syndromes ... Hypothalamic or thalamic syndromes ... (Systemic lupus ... Sjögren syndrome ... #neurology #symptoms
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Sclerosis Diagnosis ... Signs and symptoms ... #sclerosis #diagnosis ... #management #neurology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... dermatomyositis, Sjogren syndrome ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... signs and/or symptoms ... sclerosis (MS) ... #diagnosis #management ... #neurology #differential
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... Inflammatory: ... , Systemic sclerosis ... MCTD, Sjogren syndrome ... #diagnosis #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
sclerosis Pathophysiology ... brainstem and multiple ... (3) primary lateral ... #Sclerosis #neurology ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... purpura: Strong sign ... Mucocutaneous lymph node syndrome ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
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