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management algorithm anemia apml classification common cvid focal gap globulin hemolytic hypogammaglobulinemia immunodeficiency immunology lad localized lymphadenopathy protein proteingap syndrome
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... : • Liver disease ... Hemolytic #Anemia #Differential ... #Diagnosis #causes ... classification #hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Diagnosis Algorithm ... , Mediastinum, Lungs ... #Causes #Hematology ... #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation ... HoTN, edema and effusions ... initiation • Differential ... #management #hematology ... #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
impaired B-cell differentiation ... • Chronic lung ... disease • Liver ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Sarcoidosis) • Liver ... ovarian tumors, lung ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
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