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diagnosis management differential rheumatology causes hematology nephrology neurology oncology rhabdomyolysis activation antibodies associations autoantibodies behcet bloodsmear borrelia calcium castleman cauda
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Anticentromere - CREST syndrome ... Anti-Scl-70 - Scleroderma ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... #diagnosis #table
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
intracranial pressure • Dialysis ... disequilibrium syndrome ... Inhibitors of Na+K+2Cl ... Tolvaptan) • Treatment ... #Medications #Table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... disease 2. ... urine output: 200 ml ... per day until stable ... Dialysis for severe
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... aseptic meningitis), MCC ... : Arterial (MCC-small ... tests in Behcet syndrome ... Arthritis, AS Treatment
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... oxidative iniury Treatment ... per day until stable ... Dialysis for severe
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelogenous Leukemia (CML ... Myeloproliferative Disease ... factor (GCSF) treatments ... appear normal, but analysis ... marrow studies Treatment
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... blood gas (ABC) analysis ... ) on room air Treatment ... hepatopulmonary #syndrome ... diagnosis #management #treatment
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
Cauda Equina Syndrome ... Cauda Equina Syndrome ... lumbar spine • MCC ... dysfunction SPINE Mnemonic ... axial T1 and T2 Treatment
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Anti-GAD Ab (>1000u/ml ... poisoning, Parkinson's disease ... Treatment: • ... Baclofen • Severe Disease ... Diagnosis #Management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... Periodic fever syndromes ... 5000 to 10,000 ng/mL ... Treatment: • Corticosteroids
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