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diagnosis erythematosus rheumatology management neurology systemic approach arthritis cerebritis clues cns complications hypersensitivityreaction immunology joint musculoskeletal myelitis pain signs symptoms
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
: • Systemic Lupus ... Erythematosus (SLE ... antigens are the cause ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... Myopathy (Also caused ... #MSK #Musculoskeletal ... Complications #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... inflammation, leading ... Erythematosus #SLE
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... the face (many differential ... 3) Limb oedema leading ... children (pediatric SLE ... #diagnosis #sle
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... Like in this case ... Chronic = RA, SLE ... #Joint #Pain #MSK ... approach #workup #differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Evaluate for NMO, SLE ... • Infectious causes ... Disorders: - SLE ... management #neurology #differential
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