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diagnosis rheumatology classification management types hypersensitivity reactions table activation cerebritis clues comparison complications cryoglobulinemia cryoglobulins hematology hypersensitivityreaction immunology macrophage mas
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... #Lupus #Erythematosus ... #SLE #CNS #neurology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... #Lupus #Erythematosus ... #SLE #MSK #Musculoskeletal ... Complications #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
: • Systemic Lupus ... • Erythematosus ... (SLE) If bacterial ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... cellular antigen, leading ... arthritis, and systemic ... lupus erythematosus ... Classification #Pathophysiology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
3) Limb oedema leading ... children (pediatric SLE ... #diagnosis #sle ... #clues #system ... #erythematosus #
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
lgE causes mast-cell ... cell antigens, leading ... glomerulonephritis, Systemic ... lupus erythematosus ... reactions #types #allergy
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
IL-1 and IL-6, leading ... lupus erythematosus ... (CNS) dysfunction ... lupus erythematosus ... [SLE], AOSD) •
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... , leading to the ... • They can cause ... Cryoglobulins Cause ... lupus erythematosus
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
disorders, including systemic ... lupus erythematosus ... (SLE), Sjögren’ ... cell lymphoma Pathophysiology ... and the systemic
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