10 results
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphomas and Lymphoproliferative ... Disorders - Differential ... Hodgkin Lymphoma ... Depletion Non-Hodgkin lymphomas ... @AmyChung #Lymphomas
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Workup: • Full ... Immunohistochemical studies (to differentiate ... #diagnosis #classification ... #hematology #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Hodgkin's Lymphoma ... Non-Hodgkin's Lymphoma ... Comparison Hodgkin's Lymphoma ... • Malignant lymphoma ... #diagnosis #differential
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Diagnosis Algorithm ... Congestive • Cirrhosis ... Malignant • Lymphoma ... Myeloproliferative disorders ... #Causes #Hematology
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
- Differential ... Diagnosis Algorithm ... Drugs, Endocrine disorders ... High 1, 25 VitD: Lymphoma ... #Workup #nephrology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
the non-Hodgkin lymphoma ... • Follicular lymphoma ... Marginal zone lymphoma ... • Mantle cell lymphoma ... #workup #oncology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... bile ducts Differential ... Diagnosis: • ... Endocrinopathy, Lymphoma ... #workup #hepatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Marginal Zone Lymphoma ... et diutinum Neurologic ... Marginal zone lymphoma ... #Monoclonal #Differential ... #Diagnosis #Oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Amyloidosis • Lymphoma ... Liver disease: Cirrhosis ... : Lymphoma, Leukemia ... #diagnosis #hematology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
Biopsy: Solitary disorder ... • Non-Hodgkin Lymphoma ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology