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oncology lad lymphadenopathy approach chronic cll disorders globulin infections infectiousdiseases localized lymphocytic lymphomas mds mycobacteria myelodysplasia myelodysplastic nonhodgkin nontuberculous ntm
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... Diagnosis Algorithm ... #Focal #Localized ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Diagnosis Algorithm ... Fatigue • Acute ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Infectious: • Acute ... Iron deficiency anemia ... #Diagnosis #Algorithm ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm ... Blood Loss • Acute ... #Classification ... #Diagnosis #Algorithm ... #Causes #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... lymphadenopathy more diffuse ... Treated Like Acute ... Leukemias, very ... pathophysiology #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Cytopenias: • Neutropenia ... , anemia, thrombocytopenia ... ’s lymphoma or acute ... #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... - infiltrates (anemia ... or functional neutropenia ... #Hematology #Oncology ... #Diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia ... #ProteinGap #differential ... #diagnosis #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease • Neutropenia ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... grp I-III): Pulmonary ... grp IV): Pulmonary ... Bone Marrow - Anemia ... , neutropenia
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