21 results
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
LeserTrelat #Sign #PhysicalExam ... #clinical #video ... #skin #dermatology ... #oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Cryoglobulinemia Renal-centered ... immunotactoid GN, Type I cryo ... Differential #Diagnosis #hematology ... #oncology
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
vasculitis - Skin ... test Most Common Clinical ... Wide variety of skin ... (e.g. uveitis, retinal ... Diagnosis #criteria #rheumatology
Molluscum Contagiosum on Ocular Exam

Small, firm, raised papules on the skin with umbilicated (dimpled) center.

#Molluscum #Contagiosum
Contagiosum on Ocular ... papules on the skin ... #PhysicalExam # ... skin #dermatology ... #clinical #video
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
pulmonary emboli, and ocular ... thrombi including retinal ... Diagnosis: • + Clinical ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Restrictive lung defect ... Abdominal pain (20%) Renal ... symptoms #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... ulceration • Ocular ... Behcet syndrome (Clinical ... damage) • Skin ... signs #symptoms #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... , retinal, DVT, ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Mechanisms: • Direct ... Aplastic Anemia Clinical ... Headaches • Pale skin ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ulcers, cutaneous, ocular ... Syndrome: - Ocular ... pattern: antibodies directed ... pattern: is usually directed ... differential #diagnosis #rheumatology