187 results
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Skin Disease: Discoid ... • Non-Scarring Alopecia ... Nail pitting), Alopecia ... , Traction alopecia ... totalis, Alopecia
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Hair Loss (Alopecia ... • Androgenetic alopecia ... facial hair) • Alopecia ... Disease • Discoid ... Brocq • Alopecia
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... areas -> Scaring alopecia ... follicular plugging -> Discoid ... mechanism) -> Alopecia ... Phenomenon #Lupus #SLE
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Malar rash • SLE ... IBD • RA • SLE ... Psoriatic arthritis Discoid ... skin lesions • Discoid ... erythematosus • SLE
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
: Non-scarring alopecia ... Subacute cutaneous or discoid ... Classification #Criteria #SLE
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Malar Rash D Discoid ... #IMDAMNSHARP #sle
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... Photosensitivity, Alopecia ... are evocative of SLE ... management of SLE ... Lupusreference #SLE
Primary Dermatologic Nail Disorders - Differential Diagnosis Algorithm
Nail Plate - Pitting
 • Psoriasis
 • Alopecia Areata
Nail
Psoriasis • Alopecia ... Telangiectasia • SLE
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... autoantibodies • Discoid ... and permanent alopecia ... • Nonscarring alopecia ... : Drug induced SLE
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... Photosensitivity, Alopecia ... are evocative of SLE ... management of SLE ... druginduced #lupus #sle