18 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... Findings Risk ... Apolipoprotein E4 allele Risk ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
transfused patientsl • Risk ... factors: Critical ... without other cause ... transfused patients • Risk ... #diagnosis #comparison
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
injection sites) ↑ Risk ... , ESRD Pathophysiology ... : • Clinical Suspicion ... non-heparin A/C if clinical ... Management #Treatment #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Attempt if high risk ... symptoms, or> 1 ... organ dysfuxtion, ICU ... #management #hematology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Risk Factors and ... Prognostic Markers • Risk ... no consensus on risk ... Risk of recurrence
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
GrepMed Handbook Clinical ... Acute Diarrhea (>3 BM ... Perforation) Pathophysiology ... immunocompromised, IBD) • ↑Risk ... Lowest Risk: Tetracyclines
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... pneumonia • DM risk ... Lung Abscess Pathophysiology ... : 1. ... Lung Abscess - Clinical
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
increased infection risk ... • Affects 1:25,000 ... and 1:50,000 patients ... to 8 years Clinical ... DDX - Other causes
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Relapsing-remitting course +++ Clinical ... Monoclonal gammopathy ... vascular filling +++ (risk ... Prevention of at-risk ... leak #syndrome #diagnosis
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... ALS involves: (1) ... Dysphagia- increased risk ... likelihood of this 1.