32 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
: Is the PT or APTT ... to identify the cause ... ISN Education ... #prolonged #diagnosis ... #hematology #evaluation
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... Increased red cell production ... Hemolysis #Hemolytic #Anemia ... #Workup #Hematology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
- Differential Diagnosis ... /uL Initial Workup ... iron studies, PT/aPTT ... #Algorithm #hematology ... #workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... : INR/PT, aPTT(liver ... changes), high MCV anemia ... #Causes #Workup
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... the PT and the aPTT ... synthesis (impaired production ... #diagnosis #differential ... #hematology #coagulation
Upper Extremity Dermatomes and Myotomes
Motor Function
Shoulder:
 • Abduction - C5,C6 (axillary)
 • Adduction - C6, C7,
Erb's Palsy is caused ... Anterior Shoulder Dislocation ... - May cause axillary ... Dermatomes #Myotomes #diagnosis ... #neurology #sensory
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... synthesis - Impaired production ... #diagnosis #differential ... #hematology #coagulation
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Decreased RBC Production ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential Diagnosis ... Acquired Aplastic Anemia ... #Pancytopenia #Workup ... #Algorithm #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... hemolysis, deficiency anemia ... syndrome, POEMS • Reaction ... #Differential #Diagnosis