24 results
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Non-allergic drug reaction ... dominant inherited disease ... dominant inherited disease ... cell-mediated in > 90% of cases
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
during an allergic reaction ... Or Inflammatory Reactions ... Colitis and Crohn’s Disease ... Chickenpox Other Causes ... #hematology #basophils
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Other: Transfusion reaction ... - Transfusion reaction ... Extravascular #Causes ... differential #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... syndrome, POEMS • Reaction ... Exercise, Allergic reactions
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Anemia Intrinsic Causes ... : • Liver disease ... • Transfusion reactions ... #classification ... #hematology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Allergen-specific lgE causes ... Acute transfusion reaction ... , Haemolytic disease ... allergy #table #classification
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Non-Hemolytic Transfusion Reaction ... common immune reaction ... once had another reaction ... Hemolytic Transfusion Reaction ... • Allergic reaction
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... eosinophilia (common causes ... allergy, drug reaction ... glucocorticoid treatment ... Differential #diagnosis #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Drug Reaction with ... Severe adverse drug reaction ... Edema in 70% of cases ... Exanthematous drug reaction ... : symptomatic treatment
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
common immune reaction ... once had another reaction ... Hemolytic Transfusion Reaction ... Hemolytic Transfusion Reaction ... - Allergic reaction